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Renes R Machado Selected Research

Minocycline (Cyclops)

10/2013Sex-independent suppression of experimental inflammatory pain by minocycline in two mouse strains.
5/2013A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4.

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Renes R Machado Research Topics

Disease

17Pain (Aches)
09/2023 - 12/2008
16Hyperalgesia
02/2024 - 05/2013
12Inflammation (Inflammations)
09/2023 - 06/2014
10Edema (Dropsy)
09/2023 - 06/2014
9Neuralgia (Stump Neuralgia)
02/2024 - 05/2013
6Fever (Fevers)
03/2011 - 08/2007
5Nociceptive Pain
02/2020 - 10/2013
2Type 2 Diabetes Mellitus (MODY)
02/2022 - 09/2019
2Pleurisy (Pleuritis)
02/2022 - 12/2015
1Peripheral Nervous System Diseases (PNS Diseases)
02/2024
1Pathologic Processes
01/2023
1Sepsis (Septicemia)
04/2020
1Infections
04/2020
1Pneumonia (Pneumonitis)
04/2020
1Hypersensitivity (Allergy)
04/2020
1Septic Shock (Toxic Shock Syndrome)
04/2020
1Rheumatoid Arthritis
01/2018
1Arthritis (Polyarthritis)
05/2009

Drug/Important Bio-Agent (IBA)

10CarrageenanIBA
01/2023 - 06/2014
6Paclitaxel (Taxol)FDA LinkGeneric
02/2024 - 01/2018
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2023 - 02/2008
5LipopolysaccharidesIBA
09/2023 - 08/2007
5Naltrexone (ReVia)FDA LinkGeneric
02/2020 - 06/2014
5Formaldehyde (Formol)FDA Link
12/2019 - 05/2013
4CytokinesIBA
12/2023 - 10/2008
4phthalimideIBA
01/2023 - 07/2014
4Nicorandil (SG 75)IBA
04/2018 - 05/2013
4Opioid Analgesics (Opioids)IBA
12/2015 - 02/2008
4Prostaglandins EIBA
03/2011 - 08/2007
4Indomethacin (Indometacin)FDA LinkGeneric
03/2011 - 08/2007
4ProstaglandinsIBA
03/2011 - 08/2007
4Celecoxib (Celebrex)FDA Link
05/2009 - 08/2007
3Analgesics (Analgesic Drugs)IBA
02/2024 - 12/2015
3Metformin (Glucophage)FDA LinkGeneric
12/2023 - 09/2019
3ZymosanIBA
09/2023 - 05/2009
3Niacinamide (Nicotinamide)FDA LinkGeneric
02/2020 - 05/2013
32-phthalimidethyl nitrateIBA
08/2017 - 07/2014
32-phthalimidethanolIBA
08/2017 - 07/2014
3hydroxide ionIBA
08/2017 - 07/2014
3Ibuprofen (Motrin)FDA LinkGeneric
05/2009 - 08/2007
2Clindamycin (Cleocin)FDA LinkGeneric
09/2023 - 04/2020
2Hydrogen Sulfide (Sulfide, Hydrogen)IBA
01/2023 - 08/2019
2Hypoglycemic Agents (Hypoglycemics)IBA
02/2022 - 09/2019
2Vitamin B Complex (B Vitamins)IBA
02/2020 - 10/2017
2Thiamine (Aneurin)FDA Link
02/2020 - 10/2017
2Riboflavin (Vitamin B2)FDA LinkGeneric
02/2020 - 10/2017
2Freund's AdjuvantIBA
12/2019 - 10/2017
2glutarimideIBA
12/2019 - 07/2014
2Glyburide (Glibenclamide)FDA LinkGeneric
09/2019 - 04/2018
2Cyproheptadine (Periactin)FDA Link
04/2018 - 06/2014
2Dexamethasone (Maxidex)FDA LinkGeneric
10/2017 - 05/2009
2Narcotic Antagonists (Opioid Antagonists)IBA
12/2015 - 06/2014
2Minocycline (Cyclops)FDA LinkGeneric
10/2013 - 05/2013
2Dinoprostone (PGE2)FDA Link
05/2013 - 10/2008
2Dipyrone (Metamizole)IBA
03/2011 - 05/2009
2Endothelin-1 (Endothelin 1)IBA
03/2011 - 02/2008
2AntipyreticsIBA
05/2009 - 10/2008
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
02/2008 - 08/2007
1CannabidiolIBA
02/2024
1Pregabalin (Lyrica)FDA Link
02/2024
1ThionesIBA
01/2023
1IsoindolesIBA
01/2023
1GasotransmittersIBA
01/2023
1CurcuminIBA
04/2022
1Adenosine Triphosphate (ATP)IBA
02/2022
1Potassium Channels (Potassium Channel)IBA
02/2022
1KATP ChannelsIBA
02/2020
1Therapeutic UsesIBA
09/2019
1AMP-Activated Protein KinasesIBA
09/2019
14-methylbenzenecarbothioamideIBA
08/2019
1Meloxicam (Mobic)FDA LinkGeneric
04/2018
1Leflunomide (Arava)FDA LinkGeneric
01/2018
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2017
1ChemokinesIBA
08/2017
1AntigensIBA
08/2017
1methylated bovine serum albumin (MBSA)IBA
08/2017
1CannabinoidsIBA
06/2015
1Thalidomide (Thalomid)FDA Link
07/2014
1azadirachtin (azadirachtin A)IBA
06/2014
1CationsIBA
05/2013
112S-hydroxy-1,12-pyrazolinominocyclineIBA
05/2013
1Toll-Like Receptors (Toll-Like Receptor)IBA
05/2013
1TetracyclinesIBA
05/2013
1Tetracycline (Achromycin)FDA LinkGeneric
05/2013
1Anti-Bacterial Agents (Antibiotics)IBA
05/2013
1NitratesIBA
05/2013
1Acetaminophen (Paracetamol)FDA LinkGeneric
05/2009
1Chemotactic FactorsIBA
10/2008
1QuercetinIBA
03/2008
1Prostaglandins FIBA
02/2008
1Interleukin-6 (Interleukin 6)IBA
02/2008
1mu Opioid Receptors (mu Opioid Receptor)IBA
02/2008
1Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA
02/2008
1Morphine (MS Contin)FDA LinkGeneric
02/2008
1PyrogensIBA
02/2008

Therapy/Procedure

3Injections
12/2023 - 10/2017
2Intra-Articular Injections
09/2023 - 08/2017
1Drug Therapy (Chemotherapy)
02/2024
1Analgesia
10/2013
1Subcutaneous Injections
05/2009